Japan: 45 more cases linked to asbestos exposure

March 31, 2008

TOKYO, JAPAN: A further 45 people have been confirmed with health problems after exposure to asbestos from a former factory site in Ota Ward in Tokyo, the ward office said Saturday (29 Mar).

One man in his 70s died in October of pericardial mesothelioma–a form of cancer caused by exposure to asbestos–and seven other people developed health problems after inhaling asbestos, according to the ward office.

Read complete story here.

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Advocates raise asbestos awareness

March 31, 2008

From the Oakland Press:

Each year, 10,000 Americans die — often quite painfully — due to asbestos-related illnesses. Because it takes between 10 and 50 years for symptoms to emerge, these numbers are expected to climb through 2018.

Macomb County is at increased risk because of the number of residents who work or worked in the building trades, said Michael Harbut, M.D., co-director of the National Center for Vermiculite and Asbestos-Related Cancers, at the Karmanos Cancer Institute in Detroit.

“People think asbestos is a thing of the past,” said Harbut, adding that inhaling or swallowing asbestos fibers permanently penetrates the lungs and other tissue, causing cancer and other respiratory diseases. “I wish it were.” Read the complete story here.


Phase II trial of pemetrexed and gemcitabine in chemotherapy-naive malignant pleural mesothelioma

March 20, 2008

PURPOSE: Pemetrexed and gemcitabine have single-agent activity in malignant pleural mesothelioma (MPM). The combination of pemetrexed/gemcitabine has not previously been studied in MPM to our knowledge.

PATIENTS AND METHODS: Patients with histologic or cytologic diagnosis of MPM were included. Cohort 1 received gemcitabine 1,250 mg/m(2) on days 1 and 8, with pemetrexed 500 mg/m(2) on day 8, and cohort 2 received gemcitabine 1,250 mg/m(2) on days 1 and 8, with pemetrexed 500 mg/m(2) on day 1. Cycles were repeated every 21 days; all patients were supplemented with folic acid and vitamin B(12) and received dexamethasone. Results One hundred eight patients (cohort 1, n = 56; cohort 2, n = 52) with pleural mesothelioma were enrolled. Among assessable patients, response rate was 26.0% in cohort 1 and 17.1% in cohort 2. Median time to disease progression was 4.34 months for cohort 1 and 7.43 months for cohort 2. Median survival was 8.08 months for cohort 1 (1-year survival = 31.14%) and 10.12 months for cohort 2 (1-year survival = 45.80%). In cohorts 1 and 2, incidence of grade 4 neutropenia was 25.0% and 29.4%, grade 4 thrombocytopenia was 14.3% and 3.9%, grade 3 or 4 anemia was 5.4% and 5.9%, and grade 3 or 4 fatigue was 23.2% and 15.7%, respectively.

CONCLUSION: The combination of pemetrexed and gemcitabine resulted in moderate clinical activity in MPM. However, the median survival times are similar to those with single-agent pemetrexed and inferior to outcomes observed with cisplatin in combination with an antifolate.

1: J Clin Oncol. 2008 Mar 20;26(9):1465-71, Jänne PA, Simon GR, Langer CJ, Taub RN, Dowlati A, Fidias P, Monberg M, Obasaju C, Kindler H.

Corresponding author: Pasi A. Jänne, Dana Farber Cancer Institute, Lowe Center for Thoracic Oncology, 44 Binney St, Dana D820A, Boston, MA 02115; e-mail: pjanne@partners.org.

PMID: 18349397 [PubMed – in process]


Lawsuit focuses on DuPont’s deliberate poisoning of its employees

March 14, 2008

A lawsuit in southeast Texas against DuPont is focusing on what DuPont knew and when they knew it with regard to the dangers of asbestos. Company studies showed as early as 1940, with follow-up studies in the 50’s and 60’s, that asbestos was lethal, yet the company continually and deliberately exposed its workers to the lethal fibers.

DuPont’s flimsy claim is that even though it knew asbestos was lethal, it only thought asbestos was deadly for miners and not for refinery workers. Click here to read the unbelievable claims made by this mass poisoner.


Ford Motor Company appeals record asbestos judgment in Australia

March 12, 2008

Ford Australia has lodged an appeal against a landmark decision to award a former mechanic $840,000 compensation for exposure to asbestos when he worked at Ford car dealerships. Antonino Lo Presti, 58, was the first motor mechanic in Australia to win a successful negligence verdict against a car company for exposure to asbestos, last month in the West Australian Supreme Court. Mr Lo Presti used compressed air to blow out the brake drums and handled asbestos brake linings when brakes were serviced or changed between 1970 and 1971 at two Ford dealerships he worked at.

Complete story here.

Information about mesothelioma medical and legal options provided by the Law Office of Roger G. Worthington, P.C., www.mesothel.com.