Interact Cardiovasc Thorac Surg. 2003 Mar;2(1):30-4, Malignant pleural mesothelioma: outcome of limited surgical management, Phillips PG, Asimakopoulos G, Maiwand MO.
We reviewed retrospectively 70 cases of the disease managed surgically over a 10 year period. Fifteen patients received only diagnostic direct pleural biopsy, 40 had video-assisted thoracoscopic, pleural biopsy and talc pleurodesis while 15 patients underwent thoracotomy and pleurectomy for disease confined to the pleura. There were two in-hospital deaths. Actuarial survival was significantly longer in the thoracotomy group (median 14 months vs. 6 months in the other two groups, P<0.03).
Survival after limited surgical management of malignant mesothelioma is comparable to a previously reported more radical surgical approach.
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